M.P. Coles

The paper introduces a method to directly infer protein ensembles from NOESY spectra by combining quantitative scoring, regularized selection, and molecular dynamics.

The paper investigates conformational diversity in poly-HAMP arrays and shows that axial helix rotation may be a conserved mechanism for signal transduction across different HAMP-containing systems.

The paper identifies a synthetic small molecule, C26, that inhibits HilD, a key regulator of Salmonella secretion systems, thereby preventing bacterial invasion of host cells.

This study identifies CSE as a Ca2+-binding protein that links intracellular Ca2+-signaling to cell-cell communication in multicellular cyanobacteria by regulating nanopore and septal junction formation.