MicrobiologybioRxivPreprint
Gene synteny and translational coupling of sctS and sctT facilitate assembly of the unique helical T3SS export apparatus in Salmonella Typhimurium
DOI 10.64898/2026.02.19.706803
Author
Iwan Grin
University of TübingenORCID 0000-0001-7061-9018Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagOrganism:bacteria (other)· 3Approach:experimental assay· 3Research Focus:cell signaling & trafficking· 1Research Focus:cell type annotation· 1Assay:DNA methylation· 1Research Focus:drug response / drug discovery· 1Research Focus:gene regulatory network inference· 1Research Focus:protein folding & dynamics· 1
Activity by Year
2024-2026 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 22 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- MicrobiologyScience AdvancesPeer-reviewed
Discovery of a synthetic small molecule targeting the central regulator of Salmonella pathogenicity
Abdelhakim Boudrioua, Joe D. Joiner, Iwan Grin…·Samuel Wagner
The paper identifies a synthetic small molecule, C26, that inhibits HilD, a key regulator of Salmonella secretion systems, thereby preventing bacterial invasion of host cells.
- MicrobiologyPLoS PathogensPeer-reviewed
The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors
Silke Malmsheimer, Iwan Grin, Erwin Bohn…·Samuel Wagner
This study investigates the secretion mechanism of transmembrane effector proteins by Legionella T4bSS, revealing a two-step process involving an inner membrane intermediate.
7 citations