Author
Mayo ClinicORCID 0000-0001-6730-7021Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Adarsh Rajesh, Aaron P. Havas, Rouven Arnold…·Peter D. Adams
This study shows that targeting CCND1-CDK6 reduces DNA damage, inflammation, and age-related decline in mice by suppressing SASP and ISG expression.
Anthony B. Lagnado, Yukang Li, Chibuzo Nwakama…·João F. Passos
SenoQuant is an AI software for analyzing and predicting senescence markers in tissues, offering spatial quantification across imaging modalities and supporting custom models.
Dominik Saul, Diana Jurk, Madison L. Doolittle…·João F. Passos
The paper examines p21Cip1 and p16Ink4a expression in senescent cells across tissues, revealing heterogeneity and tissue-specific SASP profiles.