Author

Lorenzo Agostini

National Institutes of HealthORCID 0000-0001-6742-4519Unclaimed ORCID profile · follow to get notified of new preprints

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Assay:electronic health records· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Christian BiertümpfeliD· 2 shared Jason A. PfisteriD· 2 shared Kevin F. O’ConnelliD· 2 shared Naoko MizunoiD· 2 shared Aurélien Perrier· 1 shared Jienyu DingiD· 1 shared Lorène BournonvilleiD· 1 shared Nirakar BasnetiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Christian BiertümpfelORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedAug 13, 2025

Structural insights into SSNA1 self-assembly and its microtubule binding for centriole maintenance

Lorenzo Agostini, Jason A. Pfister, Nirakar Basnet…·Naoko Mizuno

This study determines the cryo-EM structure of SSNA-1 and shows its self-assembly and microtubule-binding role in centriole maintenance and embryonic viability.

8 citations

C. eleganscryo-EM

𝕏 PostBluesky

Cell BiologyNature CommunicationsPeer-reviewedJun 5, 2025

The C. elegans homolog of Sjögrens Syndrome Nuclear Antigen 1 is required for the structural integrity of the centriole and bipolar mitotic spindle assembly

Jason A. Pfister, Lorenzo Agostini, Lorène Bournonville…·Kevin F. O’Connell

This study identifies SSNA-1 as a centriole constituent required for structural integrity and bipolar spindle assembly in C. elegans.

10 citations

C. eleganselectronic health records

𝕏 PostBluesky