Author

Kevin F. O’Connell

National Institutes of HealthORCID 0000-0002-9789-288XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Christian BiertümpfeliD· 2 shared Jason A. PfisteriD· 2 shared Lorenzo AgostiniiD· 2 shared Naoko MizunoiD· 2 shared Aurélien Perrier· 1 shared Carol A. MathewsiD· 1 shared Christine LöchneriD· 1 shared Dan Joseph SteiniD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

Christian BiertümpfelORCID

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3 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedAug 13, 2025

Structural insights into SSNA1 self-assembly and its microtubule binding for centriole maintenance

Lorenzo Agostini, Jason A. Pfister, Nirakar Basnet…·Naoko Mizuno

This study determines the cryo-EM structure of SSNA-1 and shows its self-assembly and microtubule-binding role in centriole maintenance and embryonic viability.

8 citations

C. eleganscryo-EM

Cell BiologyNature CommunicationsPeer-reviewedJun 5, 2025

The C. elegans homolog of Sjögrens Syndrome Nuclear Antigen 1 is required for the structural integrity of the centriole and bipolar mitotic spindle assembly

Jason A. Pfister, Lorenzo Agostini, Lorène Bournonville…·Kevin F. O’Connell

This study identifies SSNA-1 as a centriole constituent required for structural integrity and bipolar spindle assembly in C. elegans.

10 citations

C. eleganselectronic health records

NeurosciencebioRxivPreprintApr 27, 2019

Genome-wide analyses indirectly implicate miRNA regulatory mechanisms in Obsessive-compulsive Disorder psychopathology

Nathaniel W. McGregor, K O'connell, TS/ OCD PGC Workgroup…·Dan Joseph Stein

The paper investigates miRNA regulatory mechanisms in OCD by analyzing genetic variants from a meta-analysis and identifies potential indirect miRNA targets associated with OCD risk.

DOI 10.1101/601401

humanbulk RNA-seq