Author

Valerie L. Joers

Center for Translational Research in Neurodegenerative Disease, Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USAORCID 0000-0001-6743-6587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Malú G. TanseyiD· 3 shared Jianjun ChangiD· 2 shared Sean D. KellyiD· 2 shared Alexa F. Iannitelli· 1 shared Alexandra S. Coomes· 1 shared Alfonso Martín-Peña· 1 shared Ali KeshavarzianiD· 1 shared Alison R. WeissiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersNeuroscience

Malú G. TanseyORCID

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4 papers

Recent·Most cited

NeuroscienceScientific ReportsPeer-reviewedApr 21, 2025

MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson's HLA locus exhibits epigenetic regulation

Elizabeth M. Kline, Janna E. Jernigan, Christopher D. Scharer…·Valerie L. Joers

The paper investigates the role of MHCII reduction in protecting mice from alpha-synuclein-induced degeneration and finds that it is insufficient, while showing epigenetic regulation of the Parkinson's HLA locus.

1 citation

mousehuman

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BiochemistrybioRxivFeb 5, 2024

Biochemical fractionation of human α-Synuclein in a Drosophila model of synucleinopathies

Khondamir Imomnazarov, Joshua Lopez-Scarim, Ila Bagheri…·Alfonso Martín-Peña

The paper develops a protocol to assess human α-Synuclein solubility in Drosophila brains, distinguishing soluble and insoluble forms using detergent strength and sonication.

DOI 10.3390/ijms25073643

Drosophilaproteomics

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NeuroscienceJournal of NeurosciencePeer-reviewedAug 31, 2020

Transgenic mice expressing human alpha-synuclein in noradrenergic neurons develop locus coeruleus pathology and non-motor features of Parkinson's disease

Laura M. Butkovich, Madelyn C. Houser, Termpanit Chalermpalanupap…·Malú G. Tansey

This study develops a transgenic mouse model expressing human alpha-synuclein in noradrenergic neurons, revealing LC pathology and non-motor PD features.

63 citations

mouseexperimental assay

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NeurosciencebioRxivPreprintJan 30, 2020

Sexually dimorphic responses to MPTP found in microglia, inflammation and gut microbiota in a progressive monkey model of Parkinson's disease

Valerie L. Joers, Gunasingh Jeyaraj Masilamoni, Doty Kempf…·Malú G. Tansey

This study investigates sex differences in inflammatory responses and gut microbiota in a progressive monkey model of Parkinson's disease following MPTP treatment.

1 citation

non-human primateproteomics

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