Author

Richard Howard Little

John Innes CentreORCID 0000-0001-6763-1649Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:plant (other)· 1

Frequent Co-Authors

Jacob G. MaloneiD· 2 shared Catriona M. A. ThompsoniD· 1 shared Charles SavelleiD· 1 shared Danny WardiD· 1 shared Eva López· 1 shared Fitnat H. YildiziD· 1 shared Holger SondermanniD· 1 shared Jennifer K. Teschler· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Jacob G. MaloneORCID

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2 papers

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedDec 26, 2025

Cyclic-di-GMP controls Type III effector export and symptom development in Pseudomonas syringae infections via the export ATPase HrcN

Danny Ward, Richard Howard Little, Catriona M. A. Thompson, Jacob G. Malone

This study shows that cyclic-di-GMP binding to HrcN regulates effector secretion and symptom development in Pseudomonas syringae infections.

1 citation

plant (other)proteomics

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedJun 3, 2025

Secreted retropepsin-like enzymes are essential for stress tolerance and biofilm formation in Pseudomonas aeruginosa

Justin D Lormand, Charles Savelle, Jennifer K. Teschler…·Holger Sondermann

This study identifies three secreted retropepsin-like proteases in Pseudomonas aeruginosa essential for stress tolerance and biofilm formation, with implications for therapeutic strategies against bacterial infections.

1 citation

bacteria (other)proteomics

𝕏 PostBluesky