Jacob G. Malone

The paper investigates how antibiotic resistance affects the MexT regulatory switch in Pseudomonas aeruginosa, leading to phenotypic plasticity in virulence and antibiotic resistance.

This study shows that cyclic-di-GMP binding to HrcN regulates effector secretion and symptom development in Pseudomonas syringae infections.

This study identifies BatR as a regulator of biofilm formation and antibiotic tolerance in Pseudomonas aeruginosa, showing its interaction with SrkA and role in eDNA release and pyocyanin production.

This study investigates how Arabidopsis arenosa adapts to serpentine soils by shaping its associated microbiome, identifying specific microbial variants linked to plant adaptation.

This study identifies three secreted retropepsin-like proteases in Pseudomonas aeruginosa essential for stress tolerance and biofilm formation, with implications for therapeutic strategies against bacterial infections.

The paper identifies echinacoside as a tobramycin potentiator that reduces c-di-GMP levels and aggregate size in Pseudomonas aeruginosa, enhancing antibiotic efficacy against biofilms.

This study identifies 3,7-dihydroxytropolone as a new antimicrobial compound produced by Pseudomonas, revealing its biosynthesis pathway and ecological relevance.

This study identifies PA3049, renamed BatR, as a key regulator of antibiotic tolerance in Pseudomonas aeruginosa biofilms, showing its role in stress response and antimicrobial resistance.

The paper presents a low-cost genomic DNA extraction method for soil samples, which produces high-quality DNA suitable for amplicon sequencing and downstream applications at a lower cost than commercial kits.