Author

Thomas Copie

UNSW SydneyORCID 0000-0001-6766-0116Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Emma SiereckiiD· 2 shared Yann GambiniD· 2 shared Colin Louis MastersiD· 1 shared Daryan KempeiD· 1 shared Derrick LauiD· 1 shared Eve Jary· 1 shared Justin HouxiD· 1 shared Maté BiroiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Emma SiereckiORCID

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2 papers

Recent·Most cited

NeuroscienceACS Chemical NeurosciencePeer-reviewedAug 28, 2024

Single molecule fingerprinting reveals different growth mechanisms in seed amplification assays for different polymorphs of alpha Synuclein fibrils.

Derrick Lau, Yuan Tang, Vijaya B. Kenche…·Emma Sierecki

The paper uses single molecule techniques to show that different alpha-synuclein polymorphs have distinct growth mechanisms in seed amplification assays, with one polymorph showing increased secondary nucleation.

6 citations

experimental assay

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Molecular BiologybioRxivPreprintMay 5, 2024

Quantification of nanocondensates formation at the single molecule level

Justin Houx, Thomas Copie, Yann Gambin, Emma Sierecki

This study uses single molecule fluorescence spectroscopy to quantify nanocondensate formation, revealing faster and lower concentration-dependent phase separation of TDP-43 than previously observed by microscopy.

2 citations

proteomicsstatistical model

𝕏 PostBluesky