Rapid Single-Shot Synthesis of the 217 Amino Acid-Long N-Terminal Domain of Pyocin S2
Azin Saebi, Joseph S. Brown, Victoria M. Marando, Nina Hartrampf, Nicole M. Chumbler, Stephanie Hanna, Mackenzie Poskus, Andrei Loas, Laura L. Kiessling, Deborah Tan Hung, Bradley L. Pentelute
The paper synthesizes a 217 amino acid-long N-terminal domain of pyocin S2 using automated fast-flow peptide synthesis, achieving rapid production and selective uptake in Pseudomonas aeruginosa.
ACS Chemical Biology · Feb 23, 2023Peer-reviewedSynthetic Biology