Author

Soumitra Ghosh

GenentechORCID 0000-0001-6785-6362Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Amy E. EastoniD· 1 shared Arianna S MossiD· 1 shared Baris BingoliD· 1 shared Candance Wong· 1 shared Fredric P. ManfredssoniD· 1 shared Hai NguiD· 1 shared Han LiniD· 1 shared Jennifer Sanchez· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Amy E. EastonORCID

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2 papers

Recent·Most cited

NeuroscienceDiscover NeurosciencePeer-reviewedAug 27, 2026

Intranigral injection of Alpha-Synuclein pre-formed fibrils leads to BBB compromise and Bilateral Dopaminergic Neurodegeneration in A53T Alpha-Synuclein transgenic mice.

Soumitra Ghosh, Han Lin, Sarah Chu…·William J. Meilandt

This study develops a mouse model of Parkinson's disease by injecting alpha-synuclein pre-formed fibrils, leading to bilateral dopaminergic neurodegeneration and BBB compromise.

1 citation

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 13, 2019

α-synuclein aggregates induce c-Abl activation and neurodegeneration by a redox stress mechanism

Soumitra Ghosh, Seok Joon Won, Rebecca Fong…·Raymond A. Swanson

This study shows that α-synuclein aggregates cause c-Abl activation via redox stress, leading to neurodegeneration, and that N-acetyl cysteine can block this process in Parkinson's disease models.

1 citation

mouseexperimental assay

𝕏 PostBluesky