Caenorhabditis elegans LET-413 Scribble is essential in the epidermis for growth, viability, and directional outgrowth of epithelial seam cells
Amalia Riga, Janine Cravo, Ruben Schmidt, Helena R. Pires, Victoria G. Castiglioni, Sander van den Heuvel, Mike Boxem
This study identifies LET-413's role in C. elegans epidermal development, showing its necessity for growth, viability, and directional outgrowth of seam cells through interactions with DLG-1 and Rho GTPases.
PLoS Genetics · Oct 21, 2021Peer-reviewedDevelopmental Biology