Mike Boxem

This study identifies GCK-4 as a regulator of apical actin and junction organization in C. elegans intestine lumen formation, showing it acts independently of ERM phosphorylation.

The paper identifies a novel fungal peptide from Ophiocordyceps that binds to scramblase channels in ants, disrupting motor coordination and olfactory systems.

The paper identifies PAC-1 and LGL-1 as redundant inhibitors of apical polarity in C. elegans embryonic epidermis through genetic analysis.

This study identifies ULP-2/SET-26 axis regulation of germline development in C. elegans through SUMO-mediated control of H3K4me3 reader activity.

The paper introduces the mIAA7 degron, which enhances auxin-mediated protein degradation efficiency in C. elegans, with some improvements in leakiness when combined with the C.e.AID2 system.

This study identifies LET-413's role in C. elegans epidermal development, showing its necessity for growth, viability, and directional outgrowth of seam cells through interactions with DLG-1 and Rho GTPases.

The paper introduces CeLINC, a fluorescence-based assay to detect protein-protein interactions in C. elegans, confirming interactions among polarity regulators and showing no interactions among Scribble module proteins.

This study identifies MAGU-2 and MPZ-1 as C. elegans orthologs of Pals1 and PATJ, showing they form a Crumbs complex and are involved in apical domain formation.

The paper identifies BBLN-1 as a regulator of lumen morphology in C. elegans intestine and identifies its mammalian ortholog bublin, which can compensate for its loss.