Sander van den Heuvel

The First of Us: Ophiocordyceps use a novel scramblase-binding peptide to manipulate zombie ants

The paper identifies a novel fungal peptide from Ophiocordyceps that binds to scramblase channels in ants, disrupting motor coordination and olfactory systems.

Probing DNA damage sites reveals context-dependent and novel DNA damage response factors

This study uses engineered protein probes to track DNA damage dynamics and identify novel DNA damage response factors in living cells and animals.

Quantitative modelling of fate specification in the C. elegans postembryonicM lineage reveals a missing spatiotemporal signal

The paper uses quantitative modeling to investigate fate specification in the C. elegans postembryonic M lineage and identifies potential missing spatiotemporal signals.

Caenorhabditis elegans LET-413 Scribble is essential in the epidermis for growth, viability, and directional outgrowth of epithelial seam cells

This study identifies LET-413's role in C. elegans epidermal development, showing its necessity for growth, viability, and directional outgrowth of seam cells through interactions with DLG-1 and Rho GTPases.

Dose-dependent functions of SWI/SNF BAF in permitting and inhibiting cell proliferation in vivo

This study shows that SWI/SNF BAF complex dosage regulates cell proliferation and differentiation in C. elegans, with high levels inhibiting division and low levels promoting it.

C. elegans Runx/CBFβ suppresses POP-1(TCF) to convert asymmetric to proliferative division of stem cell-like seam cells

Normal Spindle Positioning In The Absence Of EBPs And Dynein Plus-End Tracking In C. elegans

The paper shows that dynein plus-end tracking in C. elegans depends on EBP-2, but spindle positioning remains normal without EBP proteins.