Victoria G. Castiglioni

This study shows Orsay virus infection reduces locomotion in C. elegans and alters food choice based on sensory context, with eol-1 modulating these behaviors.

The paper characterizes replication dynamics and short-term evolutionary patterns of OrV, revealing strand asymmetry, mutational filtering, and non-standard genomes.

The paper uses cryo-EM to study Orsay virus structure, revealing stochastic genome assortment and segment-specific replication dynamics in virion assembly.

This study examines how simulated microgravity affects the short-term evolutionary trajectories of Orsay virus in C. elegans, finding modest phenotypic changes and no significant virulence shifts.

The paper maps eco-evolutionary barriers to Orsay virus host range across six Caenorhabditis species by analyzing viral life cycle dynamics and host competence phenotypes.

This study examines how reduced gravity and muon flux affect viral infection and life history traits in Caenorhabditis elegans, revealing impacts on reproduction, morphology, and viral dynamics.

This study examines how simulated space conditions affect viral infection in C. elegans, finding that abiotic stressors reduce viral replication and alter host gene expression.

This study investigates how Orsay virus infection affects Caenorhabditis elegans larval development and how molting periods influence viral replication.

This study investigates how chronic Orsay virus infection in C. elegans leads to age-dependent immunity and superinfection exclusion.

This study tracks the progression of OrV infection in C. elegans, identifying four infection stages and gene expression changes, revealing virus-specific and general immune responses.

This study evolves two Orsay virus strains in C. elegans, finding slight infectivity changes, non-synonymous mutations, and non-random distribution of minor variants in polymorphic regions.

This study identifies LET-413's role in C. elegans epidermal development, showing its necessity for growth, viability, and directional outgrowth of seam cells through interactions with DLG-1 and Rho GTPases.

This study identifies MAGU-2 and MPZ-1 as C. elegans orthologs of Pals1 and PATJ, showing they form a Crumbs complex and are involved in apical domain formation.