Nebojša Janjić

This paper introduces CAptVE, a method for fluorescent aptamer-based labeling that enables molecular analysis in ultrastructurally reconstructable electron micrographs.

The paper evaluates the SomaScan proteome profiling platform using CCLE cancer cell lines, showing its ability to distinguish cell lines by proteome signatures and correlate with transcriptome data.

The paper identifies a genetic variant in PROCR that influences protein C and factor VII levels, linking it to both reduced coronary artery disease risk and increased venous thromboembolism risk through opposing inflammatory and thrombotic mechanisms.

The paper identifies 1,927 genetic associations with 1,478 plasma proteins using 10.6 million DNA variants and 3,301 individuals, revealing new drug targets and safety concerns.