Author

Brahm J. Yachnin

Rutgers, The State University of New JerseyORCID 0000-0001-6812-6329Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Organism:multiple species· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Adrie H. WestphaliD· 1 shared Ajasja LjubetičiD· 1 shared Alex J. VecchioiD· 1 shared Amanda L. LoshbaughiD· 1 shared Amelie SteiniD· 1 shared Ameya HarmalkariD· 1 shared Ana Alcaraz‐SernaiD· 1 shared Andrew Leaver‐FayiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Adrie H. WestphalORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 30, 2024

✦ In-depth digest

BindCraft: one-shot design of functional protein binders

Martin Pačesa, Lennart Nickel, Christian Schellhaas…·Bruno E. Correia

Hallucinating binders by backpropagating through AlphaFold2 weights gave, across 12 targets, binders in 10-100% of the designs tested per target, mostly at nanomolar affinity.

111 citations

multiple speciesprotein structure

𝕏 PostBluesky

BioinformaticsNature CommunicationsPeer-reviewedNov 29, 2021

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

Julia Koehler Leman, Sergey Lyskov, Steven Macauley Lewis…·Richard Bonneau

The paper presents a framework for ensuring reproducibility in bio-macromolecular modeling through automated benchmarks and a test server, demonstrating its utility for Rosetta and other tools.

26 citations

experimental assaybenchmarking

𝕏 PostBluesky