Askarbek N Orakov

The paper analyzes planetary microbiome structure and gene flow across habitats using metagenomic data, identifying generalist microbes as key drivers of gene transfer.

This study identifies nitroxoline's broad antibacterial activity against Gram-negative bacteria, its mode of action involving metal homeostasis and outer membrane disruption, and resistance mechanisms across multiple species.

The paper maps antibiotic cross-resistance and collateral sensitivity interactions using chemical genetic data and validates findings experimentally.

The paper refines enterotypes in global fecal metagenomes using fuzzy clustering and introduces an Enterotype Dysbiosis Score to assess disease associations.

GUNC detects and quantifies chimerism in prokaryotic genomes by analyzing contig lineage homogeneity, improving genome quality.