Marisa Isabell Keller

FastaLake selects compact metaproteomic databases from large sequence reservoirs by de novo peptide lookup

FastaLake constructs compact metaproteomic databases from sequence resources to improve peptide identification without requiring matched metagenomic sequencing.

Preoperative biliary stenting is associated with functional dysbiosis and impaired bile acid metabolism in pancreatic cancer - Impact of preoperative biliary stenting on gut microbiota

This study examines how preoperative biliary stenting affects gut microbiota and bile acid metabolism in pancreatic cancer patients, finding reduced diversity and impaired metabolism linked to postoperative complications.

Metalog: curated and harmonised contextual data for global metagenomics samples

Metalog manually curates and harmonises contextual metadata for 110,733 metagenomic samples from humans, animals, ocean water and other environments, linked to taxonomic profiles and SPIRE genomes.

Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations

This study shows that fecal microbial load, not disease, is the main driver of gut microbiome changes and identifies it as a major confounder in microbiome studies.

Refined Enterotyping Reveals Dysbiosis in Global Fecal Metagenomes

The paper refines enterotypes in global fecal metagenomes using fuzzy clustering and introduces an Enterotype Dysbiosis Score to assess disease associations.

Enterotypes of the human gut mycobiome

The paper identifies four stable fungal enterotypes in the human gut mycobiome, showing age preference and disease associations.