Ethan Levien

The paper investigates how many mutations are needed to evolve a new function using a Boolean-network model of genotype-phenotype maps, showing a power-law scaling with network size.

This study shows that stochastic growth fluctuations, not cell size or division, drive cell-to-cell growth variability in lymphocytic leukemia cells.

The paper models gene expression and growth dynamics during antibiotic exposure, showing that initial resource allocation variations predict divergent cell fates and survival outcomes.

This study shows that cooperative self-assembly of transcriptional regulators can improve regulatory specificity and long-term stability of synthetic gene circuits in yeast.

The paper quantifies how phenotypic variability affects microbial population fitness in fixed-size populations and shows how environmental fluctuations disrupt this relationship.