Author

Ivan Nalvarte

Karolinska InstitutetORCID 0000-0001-6828-2583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aphrodite DemetriouiD· 2 shared José InzunzaiD· 2 shared Artūras JakubauskasiD· 1 shared Bárbara Rojas-ArayaiD· 1 shared Beatričė Valatkaitė-RakštienėiD· 1 shared Birgitta Lindqvist· 1 shared Catalina M. PolancoiD· 1 shared Daiva BaltriukienėiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Aphrodite DemetriouORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 19, 2025

Identification of HLA-A, HLA-B and HLA-C triple homozygous and double homozygous donors: a path towards synthetic superdonor Advanced Therapeutic Medicinal Products

Daniel Naumovas, Bárbara Rojas-Araya, Catalina M. Polanco…·Jonathan Arias

The paper identifies HLA-A, HLA-B, and HLA-C homozygous donors in Lithuanians and uses CRISPR-Cas9 to generate synthetic superdonor profiles for regenerative medicine.

DOI 10.1101/2025.05.19.25327154

humanstatistical model

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Developmental BiologybioRxivPreprintMar 16, 2025

Alzheimer's Disease Mutations Disrupt Neural Stem Cell Fate and Early Brain Development

Yiqiao Wang, Johan Lorentz, Elyas Mohammadi…·Xiaofei Li

This study shows AD mutations impair neural stem cell fate and early brain development, leading to structural vulnerabilities that may increase AD risk later in life.

DOI 10.1101/2025.03.16.643546

mousebulk RNA-seq

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NeurosciencebioRxivPreprintJul 22, 2024

ERβ mediates sex-specific protection in the App-NL-G-F mouse model of Alzheimer's disease

Aphrodite Demetriou, Birgitta Lindqvist, Heba G. Ali…·Ivan Nalvarte

This study investigates ERβ's role in sex-specific protection against AD pathology in AppNL-G-F mice, finding ERβ activation protects both males and females, with ovariectomy increasing Aβ levels but limited overall pathology effects.

2 citations

mouseexperimental assay

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