Author

Aphrodite Demetriou

Karolinska InstitutetORCID 0009-0000-3902-3881Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ivan NalvarteiD· 2 shared Birgitta Lindqvist· 1 shared Dilsah Ezgi Yilmaz· 1 shared Elyas MohammadiiD· 1 shared Giusy PizzirussoiD· 1 shared Heba G. Ali· 1 shared Johan LorentziD· 1 shared José InzunzaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Ivan NalvarteORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMar 16, 2025

Alzheimer's Disease Mutations Disrupt Neural Stem Cell Fate and Early Brain Development

Yiqiao Wang, Johan Lorentz, Elyas Mohammadi…·Xiaofei Li

This study shows AD mutations impair neural stem cell fate and early brain development, leading to structural vulnerabilities that may increase AD risk later in life.

DOI 10.1101/2025.03.16.643546

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 22, 2024

ERβ mediates sex-specific protection in the App-NL-G-F mouse model of Alzheimer's disease

Aphrodite Demetriou, Birgitta Lindqvist, Heba G. Ali…·Ivan Nalvarte

This study investigates ERβ's role in sex-specific protection against AD pathology in AppNL-G-F mice, finding ERβ activation protects both males and females, with ovariectomy increasing Aβ levels but limited overall pathology effects.

2 citations

mouseexperimental assay

𝕏 PostBluesky