Abel Eraso‐Pichot

This study shows that astrocytic PI3Kα supports synaptic plasticity and cognitive function by regulating serine metabolism and D-serine levels necessary for NMDA receptor activation during long-term potentiation.

The paper shows that two endocannabinoids, 2-AG and AEA, signal to different cell types (neurons and astrocytes), inducing distinct synaptic regulation mechanisms.

The paper identifies two genetically-defined neuronal populations in Ndufs4KO mice that drive distinct pathological features of Leigh Syndrome.