Jason Botten

This paper develops new methods to measure defective interfering particle (DIP) activity in mammarenaviruses, identifying a surrogate marker of interference through glycoprotein expression loss.

This paper develops and validates two cost-effective immunoassays for detecting LCMV antibodies in mouse serum, showing high sensitivity and specificity across multiple timepoints.

This paper generates and validates specific monoclonal antibodies against Seoul virus proteins to aid in hantavirus research and drug development.