Scott H. Olejniczak

This study identifies a tumor-CAF continuum in Ewing sarcoma through single-cell RNA sequencing, revealing novel surface antigens as potential immunotherapeutic targets.

This study shows that blocking p38 reduces metastasis in breast cancer by reversing immune suppression in the tumor microenvironment, primarily through effects on CD8+ T cells and myeloid cells.

This study shows that endogenous CD28 signaling is essential for CAR T cell efficacy in multiple myeloma, and transient CD28 blockade may reduce toxicities without compromising long-term survival.