Author

Cédric Polesello

Centre National de la Recherche ScientifiqueORCID 0000-0001-6859-2960Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

François PayreiD· 3 shared Alexandra Mancheno-FerrisiD· 2 shared Alexia RiveroiD· 2 shared Jennifer ZanetiD· 2 shared Serge PlazaiD· 2 shared Clément ImmarigeoniD· 1 shared Dani OsmaniD· 1 shared David DepierreiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersDevelopmental Biology

François PayreORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintOct 15, 2026

Cancer cachexia overrides sex-specific traits in Drosophila

Alexia Rivero, Margaux Techer, Nourhene Ammar…·Cédric Polesello

This study shows that cancer cachexia in Drosophila reduces sex-specific differences in gene expression and metabolic profiles, leading to a shared molecular cachexic state.

DOI 10.64898/2026.10.09.757864

Drosophilabulk RNA-seq

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GenomicsbioRxivPreprintJan 3, 2023

Crosstalk between chromatin and the transcription factor Shavenbaby defines transcriptional output along the Drosophila intestinal stem cell lineage.

Alexandra Mancheno-Ferris, Clément Immarigeon, Alexia Rivero…·Cédric Polesello

The paper identifies how Shavenbaby isoforms regulate gene expression and chromatin structure during Drosophila intestinal stem cell differentiation.

DOI 10.1101/2023.01.03.522588

DrosophilaChIP-seq

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Developmental BiologyNature CommunicationsPeer-reviewedNov 26, 2018

Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis

Jerome G. Bohere, Alexandra Mancheno-Ferris, Sandy Al Hayek…·François Payre

This study identifies Shavenbaby as a novel Hippo pathway effector critical for adult stem cell survival by activating DIAP1 to prevent apoptosis in Drosophila renal stem cells.

36 citations

Drosophilastatistical model

𝕏 PostBluesky