Jakob Hartmann

This study shows that different types of acute stressors affect future fear learning differently in mice, with shock and social defeat enhancing fear memory recall, while restraint stress does not.

This study shows that spermidine supplementation improves depression symptoms by enhancing autophagy and correcting polyamine imbalances in both humans and mice.

This study shows that SKA2-regulated hyperactive secretory autophagy contributes to neuroinflammation and neurodegeneration in Alzheimer's disease.

The paper introduces DeepOF, an open-source tool for analyzing social behavior in mice, and finds it detects distinct stress-induced social behavioral patterns.

This study investigates the role of Fkbp5 in the paraventricular nucleus of the hypothalamus in shaping the HPA axis stress response through genetic manipulations.

This study shows that stress enhances secretory autophagy via FKBP51, leading to increased MMP9 secretion and proBDNF cleavage to mature BDNF, linking stress adaptation to psychiatric disorders.

The paper identifies SNRNP35 as a trauma type-specific PTSD gene through analysis of genetically regulated gene expression in PTSD cases and controls.