Author

Aaron M. Keeler

North Carolina State UniversityORCID 0000-0001-6879-0588Unclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 1

Frequent Co-Authors

Andrew N. LowelliD· 1 shared David H. ShermaniD· 1 shared Edward KalkreuteriD· 1 shared Gavin J. WilliamsiD· 1 shared Jennifer J. Schmidt· 1 shared Kyle S. Bingham· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperSynthetic Biology

Andrew N. LowellORCID

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1 paper

Recent·Most cited

Synthetic BiologyNature CommunicationsPeer-reviewedApr 13, 2021

Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase

Edward Kalkreuter, Kyle S. Bingham, Aaron M. Keeler…·Gavin J. Williams

The paper identifies key residues in an acyltransferase that influence substrate selectivity and demonstrates how swapping structural motifs can alter substrate specificity in polyketide synthases.

41 citations

statistical model

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