Author

Gavin J. Williams

North Carolina State UniversityORCID 0000-0003-2172-9063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron M. KeeleriD· 1 shared Alissa M MeoiD· 1 shared Andrew N. LowelliD· 1 shared Cassidy L. OliverioiD· 1 shared David H. ShermaniD· 1 shared Edward KalkreuteriD· 1 shared Jennifer J. Schmidt· 1 shared Kyle S. Bingham· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperSynthetic Biology

Aaron M. KeelerORCID

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2 papers

Recent·Most cited

Engineering the effector specificity of the macrolide-sensing transcription factor MphR for the detection of sesquiterpenes

Cassidy L. Oliverio, Alissa M Meo, Stefanie H. Chen, Gavin J. Williams

The paper develops a genetically encoded biosensor to detect four sesquiterpenes by engineering the macrolide-sensing transcription factor MphR.

bioRxiv · Oct 19, 2026 · PreprintSynthetic Biology

Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase

Edward Kalkreuter, Kyle S. Bingham, Aaron M. Keeler, Andrew N. Lowell, Jennifer J. Schmidt, David H. Sherman, Gavin J. Williams

The paper identifies key residues in an acyltransferase that influence substrate selectivity and demonstrates how swapping structural motifs can alter substrate specificity in polyketide synthases.

Nature Communications · Apr 13, 2021Peer-reviewedSynthetic Biology