Author

Edward Kalkreuter

Scripps Research InstituteORCID 0000-0002-8241-4455Unclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

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Approach:statistical model· 1

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Aaron M. KeeleriD· 1 shared Andrew N. LowelliD· 1 shared David H. ShermaniD· 1 shared Gavin J. WilliamsiD· 1 shared Jennifer J. Schmidt· 1 shared Kyle S. Bingham· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperSynthetic Biology

Aaron M. KeelerORCID

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1 paper

Recent·Most cited

Synthetic BiologyNature CommunicationsPeer-reviewedApr 13, 2021

Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase

Edward Kalkreuter, Kyle S. Bingham, Aaron M. Keeler…·Gavin J. Williams

The paper identifies key residues in an acyltransferase that influence substrate selectivity and demonstrates how swapping structural motifs can alter substrate specificity in polyketide synthases.

41 citations

statistical model

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