Author

Valentin Peretroukhin

ORCID 0000-0002-0698-4755Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 3 Approach:deep learning· 3 Research Focus:benchmarking· 2 Approach:statistical model· 2 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ali PunjaniiD· 2 shared Hannah R. BridgesiD· 2 shared M. McLean· 2 shared Serena Liu· 2 shared Amit SingeriD· 1 shared Carlos Óscar S. SorzanoiD· 1 shared Christina Wang· 1 shared CryoSPARC Team· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Ali PunjaniORCID

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3 papers

Recent·Most cited

cFAR and Relative Signal: Diagnosing Preferred Orientation in Single-Particle Cryo-EM

Valentin Peretroukhin, Michael McLean, Ali Punjani

The paper introduces cFAR and Relative Signal to diagnose preferred orientation in single-particle cryo-EM, using synthetic and real datasets to validate their effectiveness.

bioRxiv · Aug 18, 2026 · PreprintBiophysics

End-to-end automation of repeat-target cryo-EM structure determination in CryoSPARC

CryoSPARC Team, Kelly Barber, Hannah R. Bridges, Suhail Dawood, Katherine Elder, Nick Frasser, Fiona Hu, Serena Liu, M. McLean, Ryan Narine, Telisha Ng, Valentin Peretroukhin, Ali Punjani, Harris Snyder, Kye Stachowski, , Nicholas Wong

This paper automates repeat-target cryo-EM structure determination in CryoSPARC, achieving high-resolution results for 21 GPCR datasets with minimal human intervention.

bioRxiv · Oct 17, 2025 · PreprintBiophysics

The Inaugural Flatiron Institute Cryo-EM Conformational Heterogeneity Challenge

Miro A. Astore, Geoffrey Woollard, David Silva-Sánchez, Wenda Zhou, Mykhailo Kopylov, Khanh Dao Duc, Roy R. Lederman, Yilai Li, Yi Zhou, Jing Yuan, Fei Ye, Quanquan Gu, Rémi Vuillemot, Slavica Jonić, Lan Dang, , Sonya M. Hanson

The paper presents a cryo-EM conformational heterogeneity challenge to evaluate and improve methods for analyzing molecular motions in heterogeneous samples.

bioRxiv · Jul 18, 2025 · PreprintBiophysics