Author

Tara M. Sebastian

Tisch Cancer InstituteORCID 0000-0001-6894-4348Unclaimed ORCID profile · follow to get notified of new preprints

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Ariele Viacava Follis· 1 shared Jarvier N. MohammediD· 1 shared Jerry E. ChipukiD· 1 shared Jesse D. GellesiD· 1 shared Jian Jun JiniD· 1 shared Mark P.A. Luna‐VargasiD· 1 shared Md Abdullah Al NomaniD· 1 shared Md Kabir· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Ariele Viacava Follis

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1 paper

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedFeb 25, 2026

A gated hydrophobic funnel within BAX binds long-chain alkenals to potentiate pro-apoptotic function

Jesse D. Gelles, Yiyang Chen, Mark P.A. Luna‐Vargas…·Jerry E. Chipuk

The paper identifies a hydrophobic funnel in BAX that binds 2t-hexadecenal, enhancing BAX activation with BIM, and shows proline 168 regulates this interaction.

2 citations

humanproteomics

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