Author

Mark P.A. Luna‐Vargas

Tisch Cancer InstituteORCID 0000-0002-2776-9552Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Ariele Viacava Follis· 1 shared Jarvier N. MohammediD· 1 shared Jerry E. ChipukiD· 1 shared Jesse D. GellesiD· 1 shared Jian Jun JiniD· 1 shared Md Abdullah Al NomaniD· 1 shared Md Kabir· 1 shared Ngoc Dung Pham· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Ariele Viacava Follis

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

A gated hydrophobic funnel within BAX binds long-chain alkenals to potentiate pro-apoptotic function

Jesse D. Gelles, Yiyang Chen, Mark P.A. Luna‐Vargas, Ariele Viacava Follis, Md Abdullah Al Noman, Md Kabir, Stella G. Bayiokos, Jarvier N. Mohammed, Tara M. Sebastian, Ngoc Dung Pham, Yi Shi, Jian Jun Jin, Richard W. Kriwacki, Jerry E. Chipuk

The paper identifies a hydrophobic funnel in BAX that binds 2t-hexadecenal, enhancing BAX activation with BIM, and shows proline 168 regulates this interaction.

Nature Communications · Feb 25, 2026Peer-reviewedCell Biology