Patricia Ann Pioli

The paper identifies isoform-level changes in ccRCC using DTU analysis, revealing subgroups with distinct survival outcomes and potential biomarkers.

This study identifies RE methylation subtypes in ccRCC linked to immune phenotypes and survival, validated across multiple cohorts.

This paper presents a streamlined protocol for generating and multi-omic analyzing human macrophages from frozen PBMCs, showing their phenotypic stability and compatibility with snRNA-seq.

The paper demonstrates that anti-CD206 CAR T cells restore dermal white adipose tissue in systemic sclerosis by targeting CD206+ macrophages and reversing their effects on adipose-derived stem cells.

This study shows RUNX1 is expressed in SSc fibroblasts and higher levels correlate with fibrosis severity, with hypomethylation and inhibitor effects supporting its role in fibrosis.

The paper characterizes single-cell transcriptomic and epigenomic features of a 3D skin-like model of systemic sclerosis, identifying fibroblast subpopulations and their interactions with macrophages.