Author

Tamar R. Abel

Dartmouth CollegeORCID 0000-0002-6519-6898Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

T. Abel2 papers

Biology Disciplines

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Genomics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

Diana M. ToledoiD· 2 shared Dillon PopovichiD· 2 shared Helen C. JarnaginiD· 2 shared Jonathan A. GarlickiD· 2 shared Michael L. WhitfieldiD· 2 shared Patricia Ann PioliiD· 2 shared Rezvan ParviziiD· 2 shared Adrian L. OblakiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Diana M. ToledoORCID

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3 papers

Recent·Most cited

Trem2*R47H and reduced TREM2 expression both mimic human Alzheimer's disease signatures in mice

T. Abel, Ravi S. Pandey, Annat Haber, Dylan T. Garceau, Michael Sasner, Kevin P. Kotredes, Gregory A. Cary, Adrian L. Oblak, Gareth R. Howell, Bruce T. Lamb, Gregory W. Carter

This study compares two mouse models of TREM2 variants, showing both mimic Alzheimer's disease signatures in similar biological domains.

bioRxiv · Dec 19, 2025 · PreprintNeuroscience

RUNX1 is Expressed in a Subpopulation of Dermal Fibroblasts and Higher RUNX1 Levels are Associated with the Severity of Systemic Sclerosis

Rezvan Parvizi, Zhiyun Gong, Helen C. Jarnagin, Diana M. Toledo, Tamar R. Abel, Dillon Popovich, Madeline J Morrisson, Sasha Shenk, Monique Hinchcliff, Jonathan A. Garlick, Patricia Ann Pioli, Michael L. Whitfield

This study shows RUNX1 is expressed in SSc fibroblasts and higher levels correlate with fibrosis severity, with hypomethylation and inhibitor effects supporting its role in fibrosis.

bioRxiv · Apr 3, 2024 · PreprintGenomics

Single-cell epigenomic dysregulation of Systemic Sclerosis fibroblasts via CREB1/EGR1 axis in self-assembled human skin equivalents

Tamar R. Abel, Noelle N. Kosarek, Rezvan Parvizi, Helen C. Jarnagin, Gretel M. Torres, Rajan Bhandari, Mengqi Huang, Diana M. Toledo, Avi Smith, Dillon Popovich, Michael Mariani, Hee-Taek Yang, Tammara A. Wood, Jonathan A. Garlick, Patricia Ann Pioli, Michael L. Whitfield

The paper characterizes single-cell transcriptomic and epigenomic features of a 3D skin-like model of systemic sclerosis, identifying fibroblast subpopulations and their interactions with macrophages.

bioRxiv · Mar 22, 2024 · PreprintGenomics