Magdalena Marek

coelsch: Platform-agnostic single-cell analysis of meiotic recombination events

The paper benchmarks single-cell methods for meiotic recombination mapping in Arabidopsis thaliana and introduces tools to detect crossovers and haplotypes from sparse sequencing data.

Sex without crossovers mimics clonal reproduction in the holocentric plant Rhynchospora tenuis

This study shows that Rhynchospora tenuis undergoes obligate achiasmy in both sexes, leading to clonal-like inheritance through post-meiotic selection and TE-driven segregation distortion.

A holocentric pangenome links karyotype evolution to meiotic recombination

The paper links karyotype evolution to meiotic recombination by analyzing holocentric genomes and crossover patterns in Rhynchospora species.

Expression quantitative trait locus mapping in recombinant gametes using single nucleus RNA sequencing

This paper develops a method to map eQTLs using snRNA-seq of gametes from a small number of heterozygous individuals, uncovering cis- and trans-eQTLs in Arabidopsis pollen nuclei.

The vast majority of somatic mutations in plants are layer-specific

The paper analyzes somatic mutations in an Apricot tree, finding most mutations are layer-specific and can lead to somaclonal phenotypic variation.

Meiotic recombination dynamics in plants with repeat-based holocentromeres shed light on the primary drivers of crossover patterning

The paper investigates meiotic recombination dynamics in a holocentric plant, finding that telomere-led pairing drives a U-shaped crossover distribution, independent of centromere organisation.