Yu Li

This study identifies Caspase-8-mediated CYLD cleavage as a mechanism promoting LPS-induced endotoxic shock and reveals CP25 as a potential biomarker.

scMagnify decomposes multi-scale gene regulatory networks from single-cell multiomics data, revealing regulatory logic in development and disease.

SOAPy is a Python package that analyzes spatial omics data to study spatial architecture, dynamics, and communication across various biological contexts.

The paper identifies a CREBZF isoform, stZF, that activates CHOP during prolonged ER stress, promoting apoptosis and suggesting CREBZF's role in the Integrated Stress Response.