Haibing Zhang

This study identifies Caspase-8-mediated CYLD cleavage as a mechanism promoting LPS-induced endotoxic shock and reveals CP25 as a potential biomarker.

This study shows that RIPK1 deficiency or K376R mutation in dendritic cells enhances antitumor immunity by improving antigen presentation and T cell activation.

scMagnify decomposes multi-scale gene regulatory networks from single-cell multiomics data, revealing regulatory logic in development and disease.

This study identifies oxidative mtDNA B-Z transitions activating ZBP1 as a key mechanism in APAP-induced liver failure and shows TH107854 can reverse this process.

SOAPy is a Python package that analyzes spatial omics data to study spatial architecture, dynamics, and communication across various biological contexts.

This study identifies RIPK1 in hepatocytes as critical for maintaining liver homeostasis during metabolic challenges, showing its role in preventing inflammation and apoptosis in mice.