Glutamate transporter xCT is important for cGAS-dependent interferon responses to DNA and to HSV-1
Julia Blay‐Cadanet, Maria Lange Pedersen, Alice Pedersen…·Christian Kanstrup Holm
This study shows that the xCT transporter regulates cGAS-dependent interferon responses to DNA and HSV-1 by controlling glutamate levels and cGAMP production.