Bastien Suire

This study uses dual human lung models to evaluate anti-tuberculosis drugs and host-directed therapies, revealing compartment-specific efficacy and immune responses.

The paper identifies PP1 and PP2A phosphatases as regulators of NLRP1 inflammasome activation, showing that environmental toxins and viral infections trigger this pathway via TAK1 and p38 kinases.

This study shows verapamil reduces inflammation in cystic fibrosis by normalizing epithelial calcium signaling and oxidative stress in zebrafish and human cells.