Author

Ilenia Cirilli

Marche Polytechnic UniversityORCID 0000-0001-6916-5426Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Giuseppe OrsomandoiD· 2 shared Michael P. ColemaniD· 2 shared Adolfo AmiciiD· 1 shared Andrea LoretoiD· 1 shared Christina Antoniou· 1 shared David BennettiD· 1 shared Elisa Merlini· 1 shared Elliot D. MockiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Giuseppe OrsomandoORCID

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2 papers

Recent·Most cited

NeuroscienceNeurobiology of DiseasePeer-reviewedJun 3, 2025

SARM1 activation induces reversible mitochondrial dysfunction and can be prevented in human neurons by antisense oligonucleotides

Andrea Loreto, Kaitlyn M. L. Cramb, Lucy McDermott…·Richard Wade‐Martins

This study shows that SARM1 activation causes mitochondrial dysfunction in human neurons, which can be reversed by nicotinamide or prevented by antisense oligonucleotides.

14 citations

humanexperimental assay

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BiochemistrybioRxivPreprintDec 28, 2023

Adaptation of a commercial NAD quantification kit to assay the base exchange activity of SARM1

Ilenia Cirilli, Adolfo Amici, Jonathan Gilley…·Giuseppe Orsomando

The paper adapts a commercial NAD quantification kit to measure SARM1 base exchange activity using an NAD analog, offering a rapid and sensitive method.

DOI 10.1101/2023.12.28.573537

experimental assay

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