Author

Michael J. Medlyn

Mayo ClinicORCID 0000-0001-6916-9937Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian T. TingiD· 1 shared Allison R. CarriD· 1 shared Daniel D. BilladeauiD· 1 shared Erica N. Krogman· 1 shared Josey MuskeiD· 1 shared Kathryn A. KnoopiD· 1 shared Larry R. PeaseiD· 1 shared Maia ZiaeeiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adrian T. TingORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintDec 25, 2025

T cells use TNF and IFNγ for paracrine killing with target discrimination programmed by pathogen-derived factors

Matthew C. Guttormson, Erica N. Krogman, Allison R. Carr…·Adrian T. Ting

The paper shows T cells can kill target cells via TNF and IFNγ in a paracrine, perforin-independent manner, with pathogen-derived factors enabling selective elimination of infected cells.

1 citation

mouseCITE-seq

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