Author

Allison R. Carr

Mayo ClinicORCID 0000-0002-1315-4215Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian T. TingiD· 2 shared Erica N. Krogman· 2 shared Matthew C. GuttormsoniD· 2 shared Nicholas D. SuniD· 2 shared Akhilesh PandeyiD· 1 shared Daniel D. BilladeauiD· 1 shared Dusan BogunoviciD· 1 shared Haidong DongiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Adrian T. TingORCID

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2 papers

Recent·Most cited

ImmunologyScience SignalingPeer-reviewedJul 7, 2026

TBK1 and IKKϵ protect target cells from IFNγ-mediated T cell killing via an inflammatory apoptotic mechanism

Nicholas D. Sun, Allison R. Carr, Erica N. Krogman…·Adrian T. Ting

This study shows that TBK1 and IKKε protect target cells from IFNγ-mediated T cell killing by suppressing inflammatory apoptosis and NFκB-driven inflammation.

2 citations

humanexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintDec 25, 2025

T cells use TNF and IFNγ for paracrine killing with target discrimination programmed by pathogen-derived factors

Matthew C. Guttormson, Erica N. Krogman, Allison R. Carr…·Adrian T. Ting

The paper shows T cells can kill target cells via TNF and IFNγ in a paracrine, perforin-independent manner, with pathogen-derived factors enabling selective elimination of infected cells.

1 citation

mouseCITE-seq

𝕏 PostBluesky