Author

Josey Muske

Mayo ClinicORCID 0000-0001-8875-4306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian T. TingiD· 1 shared Allison R. CarriD· 1 shared Daniel D. BilladeauiD· 1 shared Erica N. Krogman· 1 shared Kathryn A. KnoopiD· 1 shared Larry R. PeaseiD· 1 shared Maia ZiaeeiD· 1 shared Matthew C. GuttormsoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adrian T. TingORCID

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1 paper

Recent·Most cited

T cells use TNF and IFNγ for paracrine killing with target discrimination programmed by pathogen-derived factors

Matthew C. Guttormson, Erica N. Krogman, Allison R. Carr, Skylar A. Rizzo, Josey Muske, Maia Ziaee, Nicholas R. Therrien, Nicholas D. Sun, Romina Ghale, Michael J. Medlyn, Daniel D. Billadeau, Larry R. Pease, Kathryn A. Knoop, Adrian T. Ting

The paper shows T cells can kill target cells via TNF and IFNγ in a paracrine, perforin-independent manner, with pathogen-derived factors enabling selective elimination of infected cells.

bioRxiv · Dec 25, 2025 · PreprintImmunology