Hirotaka Asai

The paper shows that sleep helps maintain negativity bias after stress by shaping neural representations during sleep.

The paper shows that in mice, preconfigured engram cell ensembles during sleep correlate with learning, and postlearning synaptic changes prepare for new memories.

This study shows that silencing newborn neurons in the dentate gyrus disrupts the excitation/inhibition balance in the dorsal hippocampus, impairing cognitive flexibility in mice.

The paper introduces an improved CNMF-based algorithm for calcium imaging data analysis, enhancing cell detection accuracy and signal quality.

The paper improves cell activity estimation in calcium imaging data using non-negative matrix decomposition with shrinkage estimation and enhanced initialization methods.