Kaoru Inokuchi

The paper demonstrates that baseline-normalized metrics are essential for accurately interpreting fear memory in mice, showing that conventional freezing scores confound locomotor activity.

This paper proposes a theoretical model of schema learning through low-dimensional neural representations formed during sleep-driven dimensionality reduction.

The paper shows that silent hippocampal engrams, which persist without memory recall, enhance the consolidation of new memories when reactivated.

The paper shows that sleep helps maintain negativity bias after stress by shaping neural representations during sleep.

This study identifies that sequential neuronal activity dynamics in the medial prefrontal cortex of mice encode procedural rules during learning.

The paper shows that in mice, preconfigured engram cell ensembles during sleep correlate with learning, and postlearning synaptic changes prepare for new memories.

The paper shows that NREM and REM sleep play distinct roles in forming inferential knowledge, with NREM organizing learned information and REM computing inferences from it.

The paper investigates brain pH and lactate levels in animal models of neuropsychiatric disorders, finding decreased pH and increased lactate levels as common features across multiple models.

This study shows that reverberatory activity in the hippocampus links conditioned and unconditioned stimuli during memory encoding in mice.

This study shows that short-term memory (STM) can persist as a silent engram for days and can be consolidated into long-term memory through re-exposure and sleep.

The paper shows that sleep co-reactivates relevant memories, enabling their assimilation and implicit learning.

The paper introduces an improved CNMF-based algorithm for calcium imaging data analysis, enhancing cell detection accuracy and signal quality.

The paper identifies a specific PPC cell ensemble that mediates memory updating by interacting with the anterior cingulate cortex during retrieval.

This study shows that adult neurogenesis in rats maintains hippocampal learning capacity by homeostatically renewing memory circuits, as evidenced by recovery after LTP saturation and modulation by neurogenesis manipulation.

This study shows that stress-induced glucocorticoid receptor activity in the amygdala modulates fear memory through GR-dependent synaptic plasticity mechanisms.

This study shows that inducing autophagy enhances memory destabilization and can overcome reconsolidation-resistant memories in animal models.

The paper improves cell activity estimation in calcium imaging data using non-negative matrix decomposition with shrinkage estimation and enhanced initialization methods.