Noriaki Ohkawa

Dual roles of idling moments in past and future memories

The paper shows that in mice, preconfigured engram cell ensembles during sleep correlate with learning, and postlearning synaptic changes prepare for new memories.

A novel micro-ECoG recording method for recording multisensory neural activity from the parietal to temporal cortices in mice

This paper develops a novel micro-ECoG device and surgical technique to record multisensory neural activity from the parietal to temporal cortices in mice.

Activation of prefrontal parvalbumin interneurons ameliorates treatment-resistant working memory deficit even under continuous antipsychotic treatment in a mouse model of schizophrenia

This study shows that activating prefrontal parvalbumin interneurons improves working memory deficits in a mouse model of schizophrenia, even when mice are continuously treated with antipsychotics.

HOTARU: Automatic sorting system for large scale calcium imaging data

The paper introduces an improved CNMF-based algorithm for calcium imaging data analysis, enhancing cell detection accuracy and signal quality.

Cortical cell ensemble control of past experience-dependent memory updating

The paper identifies a specific PPC cell ensemble that mediates memory updating by interacting with the anterior cingulate cortex during retrieval.

Adult Neurogenesis Conserves Hippocampal Learning Capacity

This study shows that adult neurogenesis in rats maintains hippocampal learning capacity by homeostatically renewing memory circuits, as evidenced by recovery after LTP saturation and modulation by neurogenesis manipulation.

Automatic sorting system for large calcium imaging data

The paper improves cell activity estimation in calcium imaging data using non-negative matrix decomposition with shrinkage estimation and enhanced initialization methods.