Author

Roy Elias

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Huili Li· 2 shared Nirmish SinglaiD· 2 shared Adam K. AragakiiD· 1 shared Adrianna Amaral· 1 shared Ajay M. VaghasiaiD· 1 shared Akinaru Yamamoto· 1 shared Alan Lorenzetti· 1 shared Alexander Gao· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Huili Li

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3 papers

Recent·Most cited

Epithelial to mesenchymal transition and M2 macrophages drive aggressiveness in murine and human sarcomatoid urothelial carcinoma.

Yujiro Hayashi, Roy Elias, Eugene Douglass, Akinaru Yamamoto, Matthew Schuler, Mingxiao Feng, Ekatherina Y. Batourina, Anne E. Geller, Woonyoung Choi, Gabriela Colocho, Alyssa G. Arbuiso, Samuel Jin, Adam K. Aragaki, Charles Ruland, Stanley Rapiey, , Burles Avner Johnson

The paper develops a murine model of sarcomatoid urothelial carcinoma (SUC) and finds it shares molecular and immunological features with human SUC, suggesting its use for therapeutic research.

bioRxiv · Oct 2, 2026 · PreprintCancer Biology

TFE3 fusions drive expression of CD44 and SPP1 in Translocation Renal Cell Carcinoma

Kaushal V. Asrani, Juhyung Woo, Thiago Vidotto, Kewen Feng, Alan Lorenzetti, Eddie L. Imada, Huili Li, Rajan Singh, Anand K Thotakura, Sangeeta Ray, Lia Oliveira, Adrianna Amaral, Vikrant Palande, Ravi Kumar Anchoori, Jayaprakash Mandal, , Tamara Lotan

The paper shows TFE3 fusions upregulate CD44 and SPP1 in tRCC, with potential therapeutic implications.

bioRxiv · Sep 22, 2026 · PreprintCancer Biology

Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1-mediated cell-intrinsic resistance

Jianyong Liu, Qing-Li He, Jianya Zhou, Ajay M. Vaghasia, Roshan Chikarmane, Glenn Hauk, Archana Rachakonda, Nicole Castagna, Ruchama C. Steinberg, Minh-Tam Pham, Jordan M. Gregg, Alok Mishra, Yuhan Yang, Talha Anwar, Roy Elias, , Srinivasan Yegnasubramanian

This paper identifies triptolide as a compound that enhances the effectiveness of DNMTi by inhibiting DCTPP1, overcoming resistance in cancer cells.

bioRxiv · May 19, 2024Cancer Biology