Luís Graça

This study shows that age-related decline in adipose tissue lipolysis reduces disease tolerance to SARS-CoV-2, increasing mortality in older mice and correlating with human COVID-19 severity.

The paper identifies a common origin for effector and regulatory CD4+ T cells in non-small cell lung cancer through single-cell analysis, revealing their plasticity and role in immune responses.

This paper develops TfR1-targeted polymersomes for colorectal cancer therapy, showing improved tumor targeting and reduced toxicity in vitro and in vivo.

The paper analyzes epigenetic and gene expression data to investigate if ME/CFS is associated with altered ACE and ACE2 levels, finding hypomethylation in ACE and ACE2 but no differential expression.