Author

Jacqueline Brockhurst

Johns Hopkins UniversityORCID 0000-0001-6946-3132Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:rat· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew S PekosziD· 2 shared Amanda R Maxwell· 1 shared Bette KorberiD· 1 shared Cheng Ting LiniD· 1 shared Cory F. BraytoniD· 1 shared Diane E. GriffiniD· 1 shared Isabelle CoppensiD· 1 shared Jerome M. EdwardsiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Andrew S PekoszORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 9, 2025

Acute induction of IFNα is responsible for the attenuation of the live measles vaccine

Jerome M. Edwards, Steve Yoon, Jacqueline Brockhurst…·Diane E. Griffin

This study identifies acute IFNα induction as the key mechanism by which the live measles vaccine is attenuated, revealing mutations in P/V/C and H genes responsible for this effect.

2 citations

humanrat

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 20, 2025

A conserved region T-cell vaccine for Sarbecoviruses

Marta Escarra‐Senmarti, Jacqueline Brockhurst, Amanda R Maxwell…·Maximillian Rosario

This paper presents a T-cell vaccine targeting conserved regions across Sarbecoviruses to provide cross-protection against evolving variants.

DOI 10.1101/2025.05.20.654373

mouserat

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